rbd's

Rare bleeding disorders (RBDs) are very rare coagulation disorders including afibrinogenemia, FII, FV, FVII, FV+FVIII, FX, FXI and FXIII deficiency. Relatively neglected until recently by health care providers, advocacy organizations and pharmaceutical companies.

 Haemophilia A and B are the most frequent inherited bleeding disorders. Together with von Willebrand disease, a defect of primary hemostasis associated with a secondary defect in coagulation factor VIII (FVIII), these X-linked disorders include 95% to 97% of all the inherited deficiencies of coagulation factors -1-.